Analytical Techniques:
- HPLC: method development, validation, troubleshooting
- Assay, identity, purity, impurities, content uniformity
- Peptide mapping
- Size analysis by SE-HPLC with DLS detection
- Particle size distribution (dynamic light scattering)
- Zeta potential determination
- pH measurement
- Loss on drying
- UV/Visible spectrometry
- Moisture content
- Forced degradation and stability studies
Material Handling and Support:
- Bench scale manufacturing; support, development, troubleshooting
- Formulation development and evaluation
- Preparation of bulk reagents
- Bench scale sample preparation and manipulation
- Cold material storage (2°C to 8°C, -20°C and -80°C)
Equipment and Instrumentation:
- Agilent 1100 HPLC (UV/Vis and DLS detection)
- Malvern Nano ZS Particle Size Analyzer; with flow through cell capability
- Varian Cary-50 UV/Visible Spectrophotometer
- AKTA Explorer protein purification system
- Osmometer
- Misonix ultrasonic cell disruption
- Hach sensION pH meter
- Rotary evaporator
- Vacuum oven
- Denver Instrument 120 Moisture analyzer
- Bronson Sonication bath
- Variable flow peristaltic pump
- Vacuum desiccators
- Analytical balance
- Top-loading balance (2kg capacity)
- HEPA-filtered clean bench
Example Analytes:
- Proteins
- Peptides
- Oligonucleotides
- Small molecules
- Tablets, solutions, lyophilisates, suspensions, powders, capsules
For Laboratory Service inquiries contact: RMCLab@rmcpharma.com |
